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Polypeptide Eye Cream

Polypeptide Eye Cream
Dr. Lara Devgan
Benefits
  • Firming
  • Lifting
  • Anti-Wrinkle
  • Renewing
  • Anti-Pigmentation
  • Mattifying
  • Plumping
  • Brightening
  • Hydrating
  • Anti-Puffiness
  • Anti-Dark Circles
  • Regenerating
  • Barrier-Strengthening
  • Cellular Anti-Ageing
  • Microbiome Balancing
  • Anti-Inflammatory
  • Anti-Redness
  • Nourishing
  • Antioxidant

Launching early September. Join the waitlist below.

The Polypeptide Eye Cream by Dr. Lara Devgan is an advanced anti-ageing treatment that targets fine lines, wrinkles, puffiness, dehydration and loss of firmness around the delicate eye area. Combining clinically proven retinoids, tetrapeptides and barrier-replenishing actives, it improves skin density, restores elasticity and reveals a smoother, brighter and more refreshed eye contour.

Retinol, Tetrapeptides and Low Molecular Weight Hyaluronic Acid form the cream's age-defying complex. Retinol accelerates cellular renewal and stimulates collagen production to soften wrinkles, while Tetrapeptides reinforce the skin's structural matrix, improving firmness and elasticity. Low Molecular Weight Hyaluronic Acid delivers deep hydration, visibly plumping wrinkles.

Caffeine, Panthenol and Lactobacillus Ferment revitalise and strengthen the delicate eye area. Caffeine energises the skin and reduces puffiness, while Panthenol reinforces barrier function and restores lasting hydration. Lactobacillus Ferment supports the skin microbiome, improving resilience and creating an optimal environment for healthier skin function.

Allantoin, Betaine and Vitamin E complete the formula with soothing, conditioning and antioxidant protection. Allantoin calms delicate skin and supports natural regeneration, Betaine maintains optimal hydration and improves suppleness, while Vitamin E protects against free radical damage to preserve collagen integrity and long-term skin health. Together, these clinically selected ingredients reveal an eye area that appears firmer, smoother, brighter and visibly revitalised.

Read more

Launching early September. Join the waitlist below.

The Polypeptide Eye Cream by Dr. Lara Devgan is an advanced anti-ageing treatment that targets fine lines, wrinkles, puffiness, dehydration and loss of firmness around the delicate eye area. Combining clinically proven retinoids, tetrapeptides and barrier-replenishing actives, it improves skin density, restores elasticity and reveals a smoother, brighter and more refreshed eye contour.

Retinol, Tetrapeptides and Low Molecular Weight Hyaluronic Acid form the cream's age-defying complex. Retinol accelerates cellular renewal and stimulates collagen production to soften wrinkles, while Tetrapeptides reinforce the skin's structural matrix, improving firmness and elasticity. Low Molecular Weight Hyaluronic Acid delivers deep hydration, visibly plumping wrinkles.

Caffeine, Panthenol and Lactobacillus Ferment revitalise and strengthen the delicate eye area. Caffeine energises the skin and reduces puffiness, while Panthenol reinforces barrier function and restores lasting hydration. Lactobacillus Ferment supports the skin microbiome, improving resilience and creating an optimal environment for healthier skin function.

Allantoin, Betaine and Vitamin E complete the formula with soothing, conditioning and antioxidant protection. Allantoin calms delicate skin and supports natural regeneration, Betaine maintains optimal hydration and improves suppleness, while Vitamin E protects against free radical damage to preserve collagen integrity and long-term skin health. Together, these clinically selected ingredients reveal an eye area that appears firmer, smoother, brighter and visibly revitalised.

Read less

15 g

$225
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More Info

  • - + Who it is for
  • - + How to Apply
  • - + Ingredients
  • - + Smell & Texture
  • - + About the Brand
  • - + Who it is for
  • - + How to Apply
  • - + Ingredients
  • - + Smell & Texture
  • - + About the Brand
Who it is for
Green tick
For you if

Loss of Firmness

Wrinkles

Dehydration

Puffiness

Dark Circles

Rosacea

Dryness

Red Cross
Not For you if
How to Apply
Apply a small amount to the under-eye area in the morning and evening. Gently pat with your ring finger until fully absorbed. Avoid direct contact with eyes. For best results, use consistently.
Ingredients

Propylene Glycol, Carbomer, Allantoin Sodium Hyaluronate, Glyceryl Stearate, Peg-100 Stearate, Cetearyl Alcohol, Petrolatum, Dimethiconc, Sorbitan Stearate, Polysorbate 60, Tocopheryl Acetate, Betaine, Butylene Glycol, Hydroryacetophenone, 1.2-Hexanediol, Phenorvethanol, EthylheryIglycerin, Panthenol, Caffeine, Tripeptide-I, Palmitoyl Tetrapeptide-7, Lactobacillus Ferment, Lactobacillus Ferment, Retinol, Fragrance, Caramel, Ci 19140, Triethanolamine.

Please note: The ingredients listed in this product are subject to change as the formulation is updated. We aim to update the INCI list as soon as possible, but we encourage you to read the ingredient list on the product itself to ensure it's suitable for your personal use.

Smell & Texture

Smell: Light and clean

Texture: Lightweight cream

About the Brand
Brand logo
Born from Dr. Lara Devgan’s celebrated Park Avenue plastic surgery practice, Scientific Beauty brings the principles of aesthetic medicine home. Think understated elegance, surgical precision and serious skin science, created to refine rather than reinvent, for skin that appears exceptionally polished, luminous and healthy.

Yale-educated and Johns Hopkins-trained, Dr. Lara Devgan is one of New York’s most renowned board-certified plastic surgeons, celebrated for an approach where art meets anatomy. Her philosophy is beautifully restrained: enhance what is naturally there, respect proportion and pursue results so refined they appear effortless. Scientific Beauty is that same philosophy, translated into skincare.

This is skincare that doesn't whisper when it comes to actives. The Vitamin C+B+E Ferulic Serum delivers an extraordinary 25% Vitamin C, while advanced formulas feature retinal, bakuchiol, peptides, niacinamide, hyaluronic acid and next-generation antioxidants. Potent concentrations meet medical-grade precision in formulas engineered for brighter, firmer, smoother and more resilient skin.

The Benefits

  • - + Firming & Lifting
  • - + Anti-Wrinkle
  • - + Renewing
  • - + Anti-Pigmentation
  • - + Sebum Regulating (Mattifying)
  • - + Plumping
  • - + Brightening (Energising)
  • - + Hydrating
  • - + Anti-Puffiness
  • - + Anti-Dark Circles
  • - + Regenerating
  • - + Skin Barrier Strengthening
  • - + Cell Communication
  • - + Microbiome Balancing
  • - + Balancing the Skin pH
  • - + Anti-Inflammatory
  • - + Anti-Redness
  • - + Reduces Trans Epidermal Water Loss
  • - + Nourishing
  • - + Antioxidant
Firming & Lifting

Firming & Lifting skincare is designed to restore strength, structure, and definition to the skin, creating a visibly tighter, more sculpted appearance. As the skin loses collagen and elasticity over time, it can begin to soften and sag, losing its natural contours. Advanced formulations work to rebuild this support from within—boosting firmness while helping to visibly lift and redefine the skin. The result is a smoother, more toned complexion with enhanced bounce and resilience, where facial contours appear sharper and elevated.

Anti-Wrinkle

Anti-wrinkle skincare is focused on both preventing and visibly reducing the formation of lines by targeting the structural and dynamic causes of wrinkles within the skin. Fine lines and deeper wrinkles develop as collagen and elastin decline, cell turnover slows and repeated facial movements create creases that become etched over time. Advanced formulations address these mechanisms through a combination of elastin-stimulating actives, smoothing peptides that help relax the appearance of expression lines, and deeply hydrating ingredients that plump the skin from within. By reinforcing the skin’s architecture while softening surface contractions and improving elasticity, anti-wrinkle skincare delivers a visibly smoother complexion.

Renewing

Renewing skincare focuses on accelerating the skin’s natural turnover cycle to reveal fresher, more refined skin beneath the surface. At the core of this process are retinoids — vitamin A derivatives that function at a cellular level to regulate gene expression, increase cell turnover, and stimulate collagen production, leading to smoother texture, improved tone, and reduced appearance of fine lines and imperfections. Phyto-retinols, plant-derived alternatives, offer a complementary approach by mimicking many of these renewal signals while being generally better tolerated, helping to enhance skin regeneration and clarity without the same level of irritation. Together, these actives promote a continuous cycle of shedding and renewal, refining the skin’s surface while supporting long-term structural improvement for a visibly brighter, more even, and rejuvenated complexion.

Anti-Pigmentation

Dealing with pigmentation means targeting melanin overproduction to reduce dark spots and prevent new ones. Melanin production can be triggered by UV exposure, pollution, hormonal changes (like during pregnancy), and inflammation (from acne or cuts). This excess pigment is then transferred to surrounding cells in epidermis called keratinocytes, which then moves to the skin's surface, causing visible dark spots.

To treat hyperpigmentation, a personalised and consistent approach is needed. Our anti-pigmentation products include lightening agents to block tyrosinase (the enzyme that creates melanin), antioxidants to fight free radicals, and ingredients to speed up skin cell turnover, removing pigmented cells. Using broad-spectrum sun protection is crucial to prevent new pigmentation during treatment.

Sebum Regulating (Mattifying)

Sebum regulation involves normalising oil production in your sebaceous glands to reduce shine, oiliness and breakouts, restoring your skin's natural balance. Overactive sebaceous glands can be triggered by internal factors like genetics, hormonal changes and stress, as well as external factors such as using stripping or overly active skincare, climate, pollution and diet. Excessive sebum production can lead to enlarged pores, acne and an oily, shiny appearance. Effective sebum regulation means using skincare products that balance oil levels without over-drying your skin, helping you achieve a clearer, more matte complexion.

Plumping

Plumping involves using active ingredients to boost the production of key structural components like collagen, the dermal-epidermal junction and glycosaminoglycans (GAGs), giving your skin more volume and density. Collagen provides structural support and firmness, while the dermal-epidermal junction, a thin connective layer, ensures smooth, wrinkle-free skin by facilitating cell communication. GAGs, like hyaluronic acid, keep your skin hydrated and plump from within. By stimulating these components, active ingredients help restore your skin's plumpness and radiance.

Brightening (Energising)

Brightening skincare involves using active ingredients to boost your blood circulation, detoxification and cellular energy. Improved blood circulation brings more essential nutrients and oxygen to your skin, while detoxification helps eliminate cell waste and impurities that can make your skin look dull. Certain active ingredients also enhance your skin's metabolism and regeneration. These combined actions restore your skin's vitality and radiant appearance, giving you a fresh, energised complexion.

Hydrating

Hydration is a fundamental part of healthy skincare, focusing on maintaining and restoring the skin’s water content. Well-hydrated skin appears plump, smooth and radiant, while dehydration can lead to dullness, tightness, fine lines and increased sensitivity.
Hydrating the skin can work through a fascinating mix of ingredients with different roles. Humectants like hyaluronic acid and glycerin act like water magnets, pulling water into the skin to instantly plump and smooth, while Natural Moisturizing Factors (NMFs)—such as urea, amino acids and sodium PCA—mimic the skin’s own hydration system, helping it hold onto water and stay balanced from within.
Adding humectants like hyaluronic acid to your routine will restore your skin's healthy glow, minimize fine lines, and provide a plumping effect.

Anti-Puffiness

Anti-puffiness skincare targets swelling around your eyes caused by fatigue or ageing. This can happen due to sagging eyelids, fluid build-up, or fat accumulation. The skin around your eyes is very delicate, skin is 5 to 7 times thinner than the rest of the face, making it more vulnerable to stress.

To reduce puffiness, focus on hydration, get enough sleep, and use eye creams with ingredients like caffeine or peptides. These help address water retention and fat build-up, giving you a fresher, more awake look.

Anti-Dark Circles

Anti-Dark Circles is a targeted approach for brighter eyes. These products address all types of dark circles: vascular (blue), pigmented (brown) and hollow (shadow).

Vascular dark circles: These blue circles result from poor blood and lymph circulation. Anti-dark circle actives such as caffeine, constricts blood vessels and boosts circulation, effectively reducing their appearance.
Pigmented dark circles: These brown circles are due to melanin accumulation, often influenced by genetics and sun exposure. Lightening actives work to diminish these pigmentation marks, revealing a more even skin tone.
Hollow dark circles: These shadows appear with aging as fat diminishes and skin sags. Peptides stimulate collagen and elastin production, plumping and firming the eye area.

Regenerating

Regenerating skincare actively stimulates the formation of new, healthier skin, working in alignment with the skin’s innate renewal processes. Central to this are growth factors—effectively encouraging the development of new skin tissue. Peptides complement this by acting as targeted messengers guiding the skin to rebuild with greater strength and structural integrity. Stem cell–derived actives further support this environment by delivering protective and regenerative signals that optimize cellular function and renewal. While these mechanisms are synonymous with advanced anti-ageing—improving firmness, elasticity and overall skin quality—they are equally valuable in addressing scarring, as they promote tissue repair, accelerate regeneration and help restore a smoother, more even skin surface.

Skin Barrier Strengthening

Strengthening your skin barrier involves replenishing the key elements in the top layer of your skin (stratum corneum), leading to a stronger and healthier barrier. These essential elements include lipids (ceramides, fatty acids, and cholesterol) and Natural Moisturizing Factors (amino acids, hyaluronic acid, etc.). Various factors, such as incorrect skincare use, seasonal changes, and aesthetic treatments, can damage your skin barrier. When this happens, your skin loses excess water through Trans Epidermal Water Loss (T.E.W.L) and becomes less capable of defending against environmental stressors, resulting in dryness, sensitivity, and irritation.

A healthy skin barrier is crucial for overall skin health as it helps prevent hydration loss, protects against environmental damage, and reduces the risk of skin conditions like eczema and acne. By strengthening your skin barrier, you ensure your skin remains well-hydrated, resilient, and protected.

Cell Communication

Cell-communicating ingredients support the skin by enhancing the dialogue between its cells, helping them function in a more intelligent and responsive way. Advanced actives such as growth factors, peptides and plant stem cells act as molecular messengers, signalling to skin cells and encouraging them to repair, regenerate and protect themselves against environmental stress and the visible effects of ageing.

When delivered topically in well-formulated skincare, these ingredients help stimulate essential processes such as collagen production, cellular renewal and barrier repair. The result is skin that appears stronger, smoother and more resilient over time. For these ingredients to perform optimally, they must also be bioavailable meaning the skin can readily recognise, absorb and utilise them. The closer an ingredient’s structure is to that of human skin cells, the more effectively it can interact with the skin’s natural biology, allowing it to deliver meaningful and visible results.

Microbiome Balancing

Microbiome Balancing skincare focuses on supporting the skin’s ecosystem through a precise combination of prebiotics, probiotics, and postbiotics—each playing a distinct and complementary role. Prebiotics act as a targeted nutrient source, feeding and promoting the growth of beneficial microorganisms to maintain balance within the skin’s microbiome. Probiotics then introduce and reinforce these beneficial bacteria, helping to strengthen the skin’s natural defenses and reduce the presence of harmful strains. Postbiotics, the bioactive compounds produced through this process, enhance overall skin function by supporting barrier strength, improving hydration, and calming inflammation. Together, this synergistic approach stabilises the skin environment, resulting in a complexion that is clearer, more resilient, and visibly healthier.

Balancing the Skin pH

Skin pH balancing involves keeping your skin's pH slightly acidic, between 4.5 and 6.5. This acidity is vital for the skin’s barrier, known as the acid mantle, which protects against harmful bacteria, pollutants, and environmental stressors while retaining hydration.

When your skin's pH is out of balance, you might experience dryness, irritation, acne, and increased sensitivity. Using skincare products that balance your skin’s pH helps preserve the acid mantle, keeping your skin healthy, hydrated, and resilient against external factors.

Anti-Inflammatory

Anti-Inflammatory skincare soothes, heal, and balance your skin, the targeted actives are designed to reduce inflammation. Inflammation is your body's natural response to injury or irritation, but continuous inflammation can lead to troublesome skin conditions like acne, rosacea, or eczema. Our anti-inflammatory skincare solutions work to soothe and calm your skin, reducing redness, swelling, and discomfort to provide much-needed relief. By strengthening your skin's barrier, these products help protect against further irritation and damage. Additionally, the anti-inflammatory actives support your skin's natural healing processes, leading to a more balanced and resilient complexion.

Anti-Redness

Anti-Redness skincare is all about reducing and preventing facial or body redness, which can result from irritation, skin conditions, compromised barriers, and hormonal changes. A targeted approach with multiple strategies works best for tackling redness. Anti-Redness formulations include active ingredients that soothe and strengthen your skin barrier. Their anti-inflammatory and antioxidant properties calm inflammation and protect against environmental irritants. Additionally, these ingredients have vasoconstrictive properties, meaning they reduce blood vessel dilation to lessen redness. Together, these actions help achieve a more even-toned, balanced complexion that's less prone to redness flare-ups.

Reduces Trans Epidermal Water Loss

Reducing Trans Epidermal Water Loss (TEWL) is key to maintaining your skin’s optimal hydration levels. By strengthening your skin’s natural barrier, these ingredients prevent water from escaping, keeping your skin well-hydrated and plump. The result is a smoother, more supple complexion with improved texture and resilience, giving you a healthier, more radiant look.

Nourishing

Nourishing skincare focuses on replenishing the skin with essential lipids, nutrients, and bioactive compounds to restore comfort, resilience, and optimal function. When the skin is depleted—whether through environmental stress, over-exfoliation, or natural ageing—it can become dry, fragile, and less able to protect itself. Nourishing formulations work to rebuild the lipid barrier using ingredients rich in fatty acids, vitamins, and antioxidants, helping to reinforce the skin’s structure while supporting repair and reducing moisture loss. By restoring what the skin lacks, this approach leaves it softer, stronger, and more supple.

Antioxidant

Antioxidant skincare is dedicated to protecting the skin against oxidative stress—one of the primary drivers of premature ageing and cellular damage—while preserving overall skin integrity and vitality. These formulations rely on potent molecules such as vitamin C, vitamin E, and polyphenols, which neutralize free radicals generated by UV exposure and environmental aggressors before they can compromise cellular structures like lipids, proteins, and DNA. Beyond defence, many antioxidants also support repair processes and enhance collagen stability, contributing to improved firmness, brightness and resilience. The result is skin that is not only shielded from ongoing damage but maintained in a healthier, more luminous state over time.

  • - + Firming & Lifting
  • - + Anti-Wrinkle
  • - + Renewing
  • - + Anti-Pigmentation
  • - + Sebum Regulating (Mattifying)
  • - + Plumping
  • - + Brightening (Energising)
  • - + Hydrating
  • - + Anti-Puffiness
  • - + Anti-Dark Circles
  • - + Regenerating
  • - + Skin Barrier Strengthening
  • - + Cell Communication
  • - + Microbiome Balancing
  • - + Balancing the Skin pH
  • - + Anti-Inflammatory
  • - + Anti-Redness
  • - + Reduces Trans Epidermal Water Loss
  • - + Nourishing
  • - + Antioxidant

Active Ingredients

  • - + Retinol (Vitamin A)
  • - + Low Molecular Weight Hyaluronic Acid
  • - + Caffeine
  • - + Tetrapeptides
  • - + Panthenol (Pro-Vitamin B5)
  • - + Lactobacillus Ferment
  • - + Allantoin
  • - + Betaine
  • - + Vitamin E
Retinol (Vitamin A)

Vitamin A also known as retinol is one of the most well proven skincare actives for treating blemishes, pigmentation, and signs of ageing. It works by speeding up cell turnover, stimulating collagen and elastin production, supporting DNA repair and regulating melanin (pigment) and sebum (oil) overproduction. This results in a smoother, firmer, more even complexion.

Low Molecular Weight Hyaluronic Acid

Low Molecular Weight Hyaluronic Acid (LMW-HA) is a smaller, more penetrative form of hyaluronic acid. Unlike high molecular weight forms that primarily hydrate the skin’s surface, LMW-HA has the ability to penetrate deeper into the epidermis, where it attracts and binds water to maintain optimal moisture levels from within. This deep hydration helps improve skin elasticity, firmness and smoothness, while reducing the appearance of fine lines and dehydration-induced wrinkles. Additionally, it enhances overall suppleness, making the complexion look plumper and more resilient. It is ideal for dehydrated, dull or mature skin, and especially those in need of long-lasting hydration and improved texture.

Caffeine

Caffeine has energising, microcirculation boosting and blood vessel constricting properties helping to quickly and effectively improve puffiness and dark circles.

Tetrapeptides

Tetrapeptides are short chains of four amino acids that play vital roles in skin care due to their ability to act as messengers within skin cells. These peptides serve as building blocks for essential proteins like collagen and elastin, which are crucial for maintaining skin elasticity and firmness. Additionally, tetrapeptides support the production of lumican, a key protein that helps anchor collagen fibres within the skin's structure.

By stimulating collagen and elastin synthesis, tetrapeptides enhance skin density and firmness. They promote the formation of a robust collagen network, which contributes to a plumping effect that improves the skin's overall appearance. This 3D effect helps to reduce the appearance of fine lines and wrinkles, resulting in smoother and more youthful-looking skin.

Panthenol (Pro-Vitamin B5)

Panthenol, also known as Pro-vitamin B5, is a potent humectant renowned for its exceptional hydrating, repairing, and soothing qualities. When applied to the skin, Panthenol converts to Coenzyme A, an enzyme crucial for skin regeneration. Its versatile benefits and compatibility with all skin types make Panthenol a preferred choice for replenishing and fortifying dehydrated and compromised skin.

Lactobacillus Ferment

Lactobacillus Ferment, a probiotic derived from the fermentation of Lactobacillus bacteria that focuses on microbiome balancing. A balanced microbiome is crucial for healthy skin as it strengthens the skin's barrier, reduces inflammation, and improves hydration, resulting in healthier and more resilient skin. It also helps maintain optimal pH levels and protects against infections.

Allantoin

Allantoin is a natural plant derivative, widely used in skincare for its soothing, hydrating, softening and healing properties.

Betaine

Betaine is a naturally occurring Amino acid obtained from sugar beets. It acts as a potent humectant (hydrator) and barrier-replenisher restoring the water balance in the skin and preventing Trans epidermal Water Loss (TEWL) leaving the skin plump, soft and wrinkle depth reduced.

Vitamin E

Vitamin E is a powerful oil-soluble antioxidant renowned for its excellent skin-protecting and replenishing properties. It helps prevent premature ageing by safeguarding skin cell membranes from damaging free radicals. Its nourishing qualities strengthen the skin barrier, enhancing resilience against environmental aggressors and improving water retention by reducing trans-epidermal water loss (TEWL). Additionally, Vitamin E has soothing effect thanks to it anti-inflammatory properties.

  • - + Retinol (Vitamin A)
  • - + Low Molecular Weight Hyaluronic Acid
  • - + Caffeine
  • - + Tetrapeptides
  • - + Panthenol (Pro-Vitamin B5)
  • - + Lactobacillus Ferment
  • - + Allantoin
  • - + Betaine
  • - + Vitamin E
Understanding Eye Puffiness

Periorbital puffiness, commonly known as eye puffiness, results from fluid accumulation in the tissues surrounding the eyes and may arise from various factors. Aging contributes to this condition as the skin and muscles around the eyes lose firmness over time. Allergies can trigger inflammation and congestion, leading to localized swelling. Dietary habits, particularly excessive salt intake, promote water retention, exacerbating puffiness. Sleep deprivation similarly results in fluid and blood retention in the periorbital area. Dehydration, either from inadequate water intake or excessive alcohol consumption, can further contribute to the condition. Genetics also play a role, as under-eye bags are sometimes hereditary.

Spotlight

Understanding Eye Puffiness

Periorbital puffiness, commonly known as eye puffiness, results from fluid accumulation in the tissues surrounding the eyes and may arise from various factors. Aging contributes to this condition as the skin and muscles around the eyes lose firmness over time. Allergies can trigger inflammation and congestion, leading to localized swelling. Dietary habits, particularly excessive salt intake, promote water retention, exacerbating puffiness. Sleep deprivation similarly results in fluid and blood retention in the periorbital area. Dehydration, either from inadequate water intake or excessive alcohol consumption, can further contribute to the condition. Genetics also play a role, as under-eye bags are sometimes hereditary.

Why I love it

  • "Dr. Lara Devgan combines the precision of aesthetic medicine with sophisticated skincare, creating formulas that deliver clinical performance whilst respecting the skin's natural function. Every product is designed to improve skin health, not simply mask concerns, making the collection a natural fit for our results-driven philosophy."

    X Natalie K-F

    Founder, Embassy of Beauty