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Global Anti-Ageing Serum

Global Anti-Ageing Serum
Demain Beauty
Benefits
  • Microbiome Balancing
  • Anti-Inflammatory
  • Barrier-Strengthening
  • Antioxidant
  • Nourishing
  • Hydrating
  • Anti-Redness
  • Anti-Wrinkle
  • Plumping

Launching mid-June. Join the waitlist below.

The Demain Beauty Global Anti-Ageing Serum is a lightweight, bi-phase treatment designed to restore skin balance, strengthen the barrier and support long-term skin longevity, combining microbiome-rebalancing ferments, prebiotic actives and deep hydration to improve resilience, reduce inflammation and protect against premature ageing.

Lactobacillus Ferment, Alpha-Glucan & Yacon Root acts as the hero postbiotic complex — helping to rebalance the skin’s microbiome, strengthen its natural defence mechanisms and reduce inflammation, supporting healthier, more resilient skin while contributing to long-term anti-ageing through improved skin function.

Radish Root Ferment acts as the microbiome protector — reinforcing the skin’s natural bacterial defences, helping to inhibit harmful microorganisms and supporting clarity, calmness and overall skin integrity.

Glycerin and Sodium Hyaluronate form the hydrating complex — drawing hydration into the skin, improving water retention and visibly enhancing plumpness, suppleness and comfort, helping to soften the appearance of fine lines caused by dehydration.

Milk Thistle Oil creates the antioxidant lipid foundation — rich in essential fatty acids and protective compounds, it helps defend against oxidative stress, reduce inflammation and reinforce the skin barrier, supporting a slower, more balanced ageing process.

Read more

Launching mid-June. Join the waitlist below.

The Demain Beauty Global Anti-Ageing Serum is a lightweight, bi-phase treatment designed to restore skin balance, strengthen the barrier and support long-term skin longevity, combining microbiome-rebalancing ferments, prebiotic actives and deep hydration to improve resilience, reduce inflammation and protect against premature ageing.

Lactobacillus Ferment, Alpha-Glucan & Yacon Root acts as the hero postbiotic complex — helping to rebalance the skin’s microbiome, strengthen its natural defence mechanisms and reduce inflammation, supporting healthier, more resilient skin while contributing to long-term anti-ageing through improved skin function.

Radish Root Ferment acts as the microbiome protector — reinforcing the skin’s natural bacterial defences, helping to inhibit harmful microorganisms and supporting clarity, calmness and overall skin integrity.

Glycerin and Sodium Hyaluronate form the hydrating complex — drawing hydration into the skin, improving water retention and visibly enhancing plumpness, suppleness and comfort, helping to soften the appearance of fine lines caused by dehydration.

Milk Thistle Oil creates the antioxidant lipid foundation — rich in essential fatty acids and protective compounds, it helps defend against oxidative stress, reduce inflammation and reinforce the skin barrier, supporting a slower, more balanced ageing process.

Read less

1 fl oz

$89
Free Delivery
($100)
Free Samples
($275)
Spend $100 more for Free Delivery

More Info

  • - + Who it is for
  • - + How to Apply
  • - + Ingredients
  • - + Smell & Texture
  • - + About the Brand
  • - + Who it is for
  • - + How to Apply
  • - + Ingredients
  • - + Smell & Texture
  • - + About the Brand
Who it is for
Green tick
For you if

Microbiome Balancing

Barrier Strengthening

Redness

Wrinkles

Loss of Volume

Dry Skin

Eczema & Psoriasis

Sensitive Skin

Reactive Skin

Rosacea

Dehydrated Skin

Red Cross
Not For you if
How to Apply
Shake the bottle before use. Apply morning and evening to skin, massaging gently into the face and neck using circular movements to encourage absorption and stimulate circulation.
Ingredients

AQUA, SILYBUM MARIANUM SEED OIL, LACTOBACILLUS/PUNICA GRANATUM FRUIT FERMENT EXTRACT, GLYCERIN (moisturizer), PENTYLENE GLYCOL, ALPHA-GLUCAN OLIGOSACCHARIDE, XYLITYLGLUCOSIDE, LEUCONOSTOC/RADISH ROOT FERMENT FILTRATE, ANHYDROXYLITOL, ASTRAGALUS MEMBRANACEUS ROOT EXTRACT, ATRACTYLODES MACROCEPHALA ROOT EXTRACT, BUPLEURUM FALCATUM ROOT EXTRACT, POLYMNIASONCHIFOLIA ROOT JUICE, STEVIOSIDE, SODIUM HYALURONATE, XYLITOL, MALTODEXTRIN, ALOE BARBADENSIS LEAF JUICE POWDER, CITRIC ACID, LACTOBACILLUS, GLUCOSE, HELIANTHUS ANNUUS SEED OIL, ALTEROMONAS FERMENT EXTRACT, PHENETHYL ALCOHOL, TOCOPHEROL, BETA-SITOSTEROL, SQUALENE.

Please note: The ingredients listed in this product are subject to change as the formulation is updated. We aim to update the INCI list as soon as possible, but we encourage you to read the ingredient list on the product itself to ensure it's suitable for your personal use.

Smell & Texture

Smell: Fragrance-Free

Texture: A bi-phase texture, lightweight with a soft oil slip.

About the Brand
Brand logo
Demain Beauty is not simply a skincare brand — it is a conviction, a movement, and a quiet revolution in the way we understand skin health. Born in France and certified organic by Ecocert's most rigorous COSMOS ORGANIC standard, every product in the Demain range is crafted with a singular belief: that beauty should never come at a cost to your health. Multi-award-winning and backed by scientifically proven results, Demain Beauty has carved its own space in the landscape of clean, conscious skincare — one that is as committed to what goes into a formula as to what is deliberately left out. With a loyal community of devotees, glowing clinical results, and a growing presence in the world's most discerning beauty circles, this is a brand that has earned its place not through noise, but through results.

The Benefits

  • - + Microbiome Balancing
  • - + Balancing the Skin pH
  • - + Anti-Inflammatory
  • - + Skin Barrier Strengthening
  • - + Antioxidant
  • - + Nourishing
  • - + Hydrating
  • - + Anti-Redness
  • - + Anti-Wrinkle
  • - + Plumping
Microbiome Balancing

Microbiome Balancing skincare focuses on supporting the skin’s ecosystem through a precise combination of prebiotics, probiotics, and postbiotics—each playing a distinct and complementary role. Prebiotics act as a targeted nutrient source, feeding and promoting the growth of beneficial microorganisms to maintain balance within the skin’s microbiome. Probiotics then introduce and reinforce these beneficial bacteria, helping to strengthen the skin’s natural defenses and reduce the presence of harmful strains. Postbiotics, the bioactive compounds produced through this process, enhance overall skin function by supporting barrier strength, improving hydration, and calming inflammation. Together, this synergistic approach stabilises the skin environment, resulting in a complexion that is clearer, more resilient, and visibly healthier.

Balancing the Skin pH

Skin pH balancing involves keeping your skin's pH slightly acidic, between 4.5 and 6.5. This acidity is vital for the skin’s barrier, known as the acid mantle, which protects against harmful bacteria, pollutants, and environmental stressors while retaining hydration.

When your skin's pH is out of balance, you might experience dryness, irritation, acne, and increased sensitivity. Using skincare products that balance your skin’s pH helps preserve the acid mantle, keeping your skin healthy, hydrated, and resilient against external factors.

Anti-Inflammatory

Anti-Inflammatory skincare soothes, heal, and balance your skin, the targeted actives are designed to reduce inflammation. Inflammation is your body's natural response to injury or irritation, but continuous inflammation can lead to troublesome skin conditions like acne, rosacea, or eczema. Our anti-inflammatory skincare solutions work to soothe and calm your skin, reducing redness, swelling, and discomfort to provide much-needed relief. By strengthening your skin's barrier, these products help protect against further irritation and damage. Additionally, the anti-inflammatory actives support your skin's natural healing processes, leading to a more balanced and resilient complexion.

Skin Barrier Strengthening

Strengthening your skin barrier involves replenishing the key elements in the top layer of your skin (stratum corneum), leading to a stronger and healthier barrier. These essential elements include lipids (ceramides, fatty acids, and cholesterol) and Natural Moisturizing Factors (amino acids, hyaluronic acid, etc.). Various factors, such as incorrect skincare use, seasonal changes, and aesthetic treatments, can damage your skin barrier. When this happens, your skin loses excess water through Trans Epidermal Water Loss (T.E.W.L) and becomes less capable of defending against environmental stressors, resulting in dryness, sensitivity, and irritation.

A healthy skin barrier is crucial for overall skin health as it helps prevent hydration loss, protects against environmental damage, and reduces the risk of skin conditions like eczema and acne. By strengthening your skin barrier, you ensure your skin remains well-hydrated, resilient, and protected.

Antioxidant

Antioxidant skincare is dedicated to protecting the skin against oxidative stress—one of the primary drivers of premature ageing and cellular damage—while preserving overall skin integrity and vitality. These formulations rely on potent molecules such as vitamin C, vitamin E, and polyphenols, which neutralize free radicals generated by UV exposure and environmental aggressors before they can compromise cellular structures like lipids, proteins, and DNA. Beyond defence, many antioxidants also support repair processes and enhance collagen stability, contributing to improved firmness, brightness and resilience. The result is skin that is not only shielded from ongoing damage but maintained in a healthier, more luminous state over time.

Nourishing

Nourishing skincare focuses on replenishing the skin with essential lipids, nutrients, and bioactive compounds to restore comfort, resilience, and optimal function. When the skin is depleted—whether through environmental stress, over-exfoliation, or natural ageing—it can become dry, fragile, and less able to protect itself. Nourishing formulations work to rebuild the lipid barrier using ingredients rich in fatty acids, vitamins, and antioxidants, helping to reinforce the skin’s structure while supporting repair and reducing moisture loss. By restoring what the skin lacks, this approach leaves it softer, stronger, and more supple.

Hydrating

Hydration is a fundamental part of healthy skincare, focusing on maintaining and restoring the skin’s water content. Well-hydrated skin appears plump, smooth and radiant, while dehydration can lead to dullness, tightness, fine lines and increased sensitivity.
Hydrating the skin can work through a fascinating mix of ingredients with different roles. Humectants like hyaluronic acid and glycerin act like water magnets, pulling water into the skin to instantly plump and smooth, while Natural Moisturizing Factors (NMFs)—such as urea, amino acids and sodium PCA—mimic the skin’s own hydration system, helping it hold onto water and stay balanced from within.
Adding humectants like hyaluronic acid to your routine will restore your skin's healthy glow, minimize fine lines, and provide a plumping effect.

Anti-Redness

Anti-Redness skincare is all about reducing and preventing facial or body redness, which can result from irritation, skin conditions, compromised barriers, and hormonal changes. A targeted approach with multiple strategies works best for tackling redness. Anti-Redness formulations include active ingredients that soothe and strengthen your skin barrier. Their anti-inflammatory and antioxidant properties calm inflammation and protect against environmental irritants. Additionally, these ingredients have vasoconstrictive properties, meaning they reduce blood vessel dilation to lessen redness. Together, these actions help achieve a more even-toned, balanced complexion that's less prone to redness flare-ups.

Anti-Wrinkle

Anti-wrinkle skincare is focused on both preventing and visibly reducing the formation of lines by targeting the structural and dynamic causes of wrinkles within the skin. Fine lines and deeper wrinkles develop as collagen and elastin decline, cell turnover slows and repeated facial movements create creases that become etched over time. Advanced formulations address these mechanisms through a combination of elastin-stimulating actives, smoothing peptides that help relax the appearance of expression lines, and deeply hydrating ingredients that plump the skin from within. By reinforcing the skin’s architecture while softening surface contractions and improving elasticity, anti-wrinkle skincare delivers a visibly smoother complexion.

Plumping

Plumping involves using active ingredients to boost the production of key structural components like collagen, the dermal-epidermal junction and glycosaminoglycans (GAGs), giving your skin more volume and density. Collagen provides structural support and firmness, while the dermal-epidermal junction, a thin connective layer, ensures smooth, wrinkle-free skin by facilitating cell communication. GAGs, like hyaluronic acid, keep your skin hydrated and plump from within. By stimulating these components, active ingredients help restore your skin's plumpness and radiance.

  • - + Microbiome Balancing
  • - + Balancing the Skin pH
  • - + Anti-Inflammatory
  • - + Skin Barrier Strengthening
  • - + Antioxidant
  • - + Nourishing
  • - + Hydrating
  • - + Anti-Redness
  • - + Anti-Wrinkle
  • - + Plumping

Active Ingredients

  • - + Lactobacillus Ferment
  • - + Milk Thistle Oil
  • - + Glycerin
  • - + Alpha Glucan
  • - + Radish Root Ferment
  • - + Yacon Root
  • - + Low Molecular Weight Hyaluronic Acid
  • - + Stevioside
Lactobacillus Ferment

Lactobacillus Ferment, a probiotic derived from the fermentation of Lactobacillus bacteria that focuses on microbiome balancing. A balanced microbiome is crucial for healthy skin as it strengthens the skin's barrier, reduces inflammation, and improves hydration, resulting in healthier and more resilient skin. It also helps maintain optimal pH levels and protects against infections.

Milk Thistle Oil

Milk Thistle Oil actively supports cellular reconstitution and barrier repair, replenishing the skin's hydrolipidic film and restoring elasticity and suppleness to skin that has become dry, depleted or visibly aged. Its high Vitamin E content neutralises free radical damage and protects against environmental oxidative stress, while its omega 6 fatty acids deeply nourish and strengthen the skin's natural resilience over time.

Glycerin

Glycerin is a potent humectant commonly used in skincare for its powerful hydrating properties. It works by attracting water molecules from the atmosphere and retaining them in the deeper layers of the skin, effectively boosting hydration reservoir. This helps to plump up the skin, resulting in reduced dehydration lines and a soft, supple complexion.

Alpha Glucan

Alpha-Glucan works to support and rebalance the skin’s microbiome rather than act as a direct corrective active. It selectively nourishes beneficial bacteria while limiting the growth of undesirable microorganisms, helping to restore microbial equilibrium, reduce sensitivity and strengthen the skin barrier over time. By reinforcing this ecosystem, it improves the skin’s resilience, supports clearer, calmer skin and enhances overall function

Radish Root Ferment

Radish Root Ferment acts as a targeted prebiotic — selectively feeding and strengthening beneficial bacteria on the skin's surface while simultaneously inhibiting the growth of pathogenic microorganisms. This dual action supports a more balanced, diverse and resilient skin microbiome, creating the conditions in which the skin's own natural defence and repair mechanisms can function optimally.

Yacon Root

A prebiotic-rich extract derived from the Yacon plant, exceptionally high in fructooligosaccharides (FOS) — naturally occurring sugars that selectively feed and diversify beneficial bacteria on the skin's surface. By nourishing the skin's microbiome rather than introducing new bacteria directly, it creates the ideal environment for a balanced, resilient skin ecosystem, helping to regulate excess sebum, calm reactivity and reinforce the barrier function.

Low Molecular Weight Hyaluronic Acid

Low Molecular Weight Hyaluronic Acid (LMW-HA) is a smaller, more penetrative form of hyaluronic acid. Unlike high molecular weight forms that primarily hydrate the skin’s surface, LMW-HA has the ability to penetrate deeper into the epidermis, where it attracts and binds water to maintain optimal moisture levels from within. This deep hydration helps improve skin elasticity, firmness and smoothness, while reducing the appearance of fine lines and dehydration-induced wrinkles. Additionally, it enhances overall suppleness, making the complexion look plumper and more resilient. It is ideal for dehydrated, dull or mature skin, and especially those in need of long-lasting hydration and improved texture.

Stevioside

Stevioside has soothing, antioxidant and skin-conditioning properties. It helps to reduce low-grade inflammation and oxidative stress within the skin, supporting a calmer, more balanced complexion while contributing to long-term skin resilience. Although sometimes associated with mild muscle-relaxing properties, its role is primarily to comfort, protect and support overall skin function

  • - + Lactobacillus Ferment
  • - + Milk Thistle Oil
  • - + Glycerin
  • - + Alpha Glucan
  • - + Radish Root Ferment
  • - + Yacon Root
  • - + Low Molecular Weight Hyaluronic Acid
  • - + Stevioside
Pre, Pro & Postbiotics

The skin's microbiome — the vast, complex community of bacteria, fungi and microorganisms that live on its surface — is one of its most powerful and most overlooked defence systems. When balanced, it regulates inflammation, protects against environmental aggressors, supports barrier function and keeps the complexion clear and resilient. When disrupted by harsh cleansers, antibiotics, pollution or stress, the consequences show up directly on the skin — as sensitivity, breakouts, redness and accelerated ageing.
Prebiotics feed and strengthen the beneficial bacteria already present on the skin, creating the conditions for a thriving, diverse microbiome. Probiotics — whether live or tyndallized — introduce beneficial bacterial strains that actively rebalance flora, calm inflammation and reinforce the skin's natural defences. Postbiotics are the bioactive byproducts produced when probiotics ferment, delivering concentrated anti-inflammatory, antioxidant and barrier-repairing benefits directly to the skin. Together, the three work in intelligent synergy — nurturing, rebalancing and fortifying the microbiome at every level for skin that is not just visibly healthier, but fundamentally stronger from the inside out.

Spotlight

Pre, Pro & Postbiotics

The skin's microbiome — the vast, complex community of bacteria, fungi and microorganisms that live on its surface — is one of its most powerful and most overlooked defence systems. When balanced, it regulates inflammation, protects against environmental aggressors, supports barrier function and keeps the complexion clear and resilient. When disrupted by harsh cleansers, antibiotics, pollution or stress, the consequences show up directly on the skin — as sensitivity, breakouts, redness and accelerated ageing.
Prebiotics feed and strengthen the beneficial bacteria already present on the skin, creating the conditions for a thriving, diverse microbiome. Probiotics — whether live or tyndallized — introduce beneficial bacterial strains that actively rebalance flora, calm inflammation and reinforce the skin's natural defences. Postbiotics are the bioactive byproducts produced when probiotics ferment, delivering concentrated anti-inflammatory, antioxidant and barrier-repairing benefits directly to the skin. Together, the three work in intelligent synergy — nurturing, rebalancing and fortifying the microbiome at every level for skin that is not just visibly healthier, but fundamentally stronger from the inside out.

Why I love it

  • What sets Demain Beauty apart is how effortlessly these formulas translate the science of the microbiome into results you can actually see and feel. Each product is built around a sophisticated pre, pro and postbiotic complex — working in genuine harmony with the skin's own ecosystem rather than disrupting it, stripping it back or overwhelming it with unnecessary actives. It is intelligent, considered skincare that respects the skin's natural intelligence in return.

    X Natalie K-F

    Founder, Embassy of Beauty